Guidelines for Preparing and Reviewing Licensing Applications for the Production of Radioisotopes

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The U.S. Nuclear Regulatory Commission (NRC or the Commission) is requesting public comment on Chapters 7-18 of Draft Interim Staff Guidance (ISG) NPR-ISG-2011-002, augmenting NUREG-1537, Part 1, "Guidelines for Preparing and Reviewing Applications for the Licensing of Non-Power Reactors: Format and Content," for the production of radioisotopes and NUREG-1537, Part 2, "Guidelines for Preparing and Reviewing Applications for the Licensing of Non-Power Reactors: Standard Review Plan and Acceptance Criteria," for the production of radioisotopes. The ISG augmenting NUREG-1537, Parts 1 & 2, Chapters 1-6 were published in the Federal Register for comment on October 13, 2011 (76 FR 63668). This draft ISG provides guidance for preparing and reviewing applications to obtain a construction permit and operating license for a radioisotope production facility.