Notice of Extension of Public Comment Period for the External Review Draft of a “Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility From Early-Life Exposure to Carcinogens”

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On September 27, 2007, the U.S. Environmental Protection Agency (EPA) released for public comment the External Review Draft of the "Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility from Early-Life Exposure to Carcinogens" (or Framework). At that time, a 60-day public comment period was announced. This notice announces a 30-day extension of the public comment period; the public comment period will end 90 days from September 27, 2007, the date of the original Federal Register Notice (72 FR 54910). Visit http://www.epa.gov/fedrgstr/EPA-GENERAL/2007/ September/Day-27/g19119.pdf) for further information. Members of the public may obtain the draft interim guidance from http:// www.regulations.gov; or http://www.epa.gov/osa/mmoaframework; or consult the person listed under FOR FURTHER INFORMATION CONTACT.