Allergenicity Assessment of Cry9C BT Corn Plant Pesticide

Короткий зміст

The Agency is soliciting input on the assessment of the potential for allergenicity of non-digestible proteins expressed as plant-pesticides. The specific case in question concerns the Cry9C insecticidal protein derived from Bacillus thuringiensis and expressed in field corn. In addition to EPA data evaluation records, the Agency is asking for comment on questions within an EPA background document regarding the use of amino acid homology, the brown Norway rat model, and other items regarding the assessment for potential allergenicity. This issue will also be one of the subjects of a FIFRA Science Advisory Panel (SAP) meeting in early February, 2000.