Octamethylcyclotetrasiloxane (D4); Draft Risk Evaluation; Science Advisory Committee on Chemicals (SACC) Peer Review; Notice of SACC Meeting; Availability of Draft Documents and Request for Comment

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The Environmental Protection Agency (EPA or Agency) is announcing that there will be two virtual public meetings of the Science Advisory Committee on Chemicals (SACC). On November 18, 2025, a preparatory meeting for the SACC to consider the scope and clarity of the draft charge questions for the peer review; and on December 2 through 5, 2025, a peer review meeting for the SACC to consider the octamethylcyclotetrasiloxane (D4) draft risk evaluation, technical support documents, and public comments. EPA is also announcing the availability of and soliciting public comment on the draft documents and charge questions that will be provided to the SACC for this peer review. The draft risk evaluation and technical support documents were prepared under the Toxic Substances Control Act (TSCA) and will be submitted to the SACC for peer review.