Draft Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS)

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EPA is announcing a 60-day public comment period for the 2010 draft document titled, "Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS)" (EPA/635/R-10/001). The draft document was prepared by the National Center for Environmental Assessment (NCEA) within the EPA's Office of Research and Development (ORD). The Toxicological Review of Inorganic Arsenic was submitted to the EPA's Science Advisory Board (SAB) for external peer review in 2005. The SAB completed its review and submitted its final report to the EPA Administrator in June 2007 (see EPA-SAB-07-008 at www.epa.gov/sab). EPA revised the Toxicological Review in response to the SAB comments. A detailed account of the SAB (2007) recommendations and EPA's response is provided in Appendix A of the 2010 draft Toxicological Review of Inorganic Arsenic. EPA has now submitted the 2010 draft Toxicological Review to the SAB for a focused peer review of EPA's responses to key SAB (2007) recommendations. EPA is also seeking a focused review by the public on EPA's interpretation and implementation of key SAB (2007) external peer review recommendations. The public