Plant-Pesticides; Proposed Exemption From the Requirement of a Tolerance Under the Federal Food, Drug, and Cosmetic Act for Nucleic Acids Produced in Plants

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This document proposes an exemption from the requirement of a tolerance under the Federal Food, Drug, and Cosmetic Act for residues of nucleic acids (i.e., deoxyribonucleic acid and ribonucleic acid) produced in plants as part of a plant-pesticide active or inert ingredient. Nucleic acids are ubiquitous in all forms of life, have always been present in human and domestic animal food and are not known to cause any adverse health effects when consumed as part of a food plant. Thus, EPA believes that a tolerance for nucleic acids produced in plants is not necessary to protect the public health.