Regulacje i polityka gospodarcza · 02/10/2002

Findings of Scientific Misconduct

Notice is hereby given that the Office of Research Integrity (ORI) and the Assistant Secretary for Health have taken final action in the following case: Heather J. Muenchen, Ph.D., University of Michigan: Based on the report of an investigation conducted by the University of Michigan (UM), Dr. Muenchen's admissions, and additional analysis conducted by ORI in its oversight review, the U.S. Public Health Service (PHS) found that Dr. Muenchen, former postdoctoral fellow at UM, engaged in scientific misconduct in research funded by National Institutes of Health (NIH) Urology Research Training Grant T32 DK07758 and SPORE grant PSO CA69568. Dr. Muenchen falsified and fabricated research data by computer manipulation of 12 Western blot analyses in three publications and two draft manuscripts. Specifically, PHS found that Dr. Muenchen: (1) Falsified Western blot data in Figures 3, 4A, and 4B in the following paper: Muenchen, H.J., Lin, D-L., Walsh, M.A., Keller, E.T., and Pienta, K.J. "Tumor necrosis factor-alpha-induced apoptosis in prostate cancer cells through inhibition of nuclear factor-[kappa]B by an I[kappa]B[alpha] `super-repressor.' " Clinical Cancer Research 6(5):1969-1977, 2000